Exploring whole-genome duplicate gene retention with complex genetic interaction analysis. Science, 2020, June 26.
Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins. Cell, 2020, June 25.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. Nat Metab 2020, June 1.
The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma. Cell Stem Cell, 2020, May 27.
Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study. Plos Medicine, 2020, May20.
Driving Innovation in Medicine
Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
Your gift to the Donnelly Centre allows researchers to explore new and innovative ideas that will transform our understanding of biology. It supports discovery that will unearth the cause of human disease, advance diagnosis and disease detection, create personalized therapies, and reverse injury through regenerative medicine.