A reference map of the human binary protein interactome. Nature 2020, Apr 8.
Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform. Nat Biotech 2020, Mar 16.
A drug discovery platform to identify compounds that inhibit EGFR triple mutants. Nat Chem Bio2020, Feb 24.
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nat Comms 2020, Feb 5.
Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Mol Cell 2020, Jan 29.
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Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
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